“Recluse” spiders have a necrotic poison that causes a sloughing off of tissue around the bite site. The wounds can be difficult to heal with a scar forming in most cases. The venom may also cause a systemic reaction. "

"The reaction may consist only of a very local and temporary skin irritation. Sometimes, however, the reaction may be serious and include the following stages: The actual bite may not be felt but within 1 to several hours the bitten area becomes painful and swollen, with blisters sometimes forming. Over a period of a few to several days the bite site becomes purple and then black as the cells die (necrosis)."

"The bite of the brown recluse spider can result in a painful, deep wound that takes a long time to heal. Fatalities are extremely rare, but bites are most dangerous to young children, the elderly, and those in poor physical condition. When there is a severe reaction to the bite, the site can erupt into a "volcano lesion" (a hole in the flesh due to damaged, gangrenous tissue). The open wound may range from the size of an adult's thumbnail to the span of a hand. The dead tissue gradually sloughs away, exposing underlying tissues. The sunken, ulcerating sore may heal slowly up to 6 to 8 weeks. Full recovery may take several months and scarring may remain"